Hormone type 6, also known as parathyroid hormone-related protein (PTHrP), is a protein hormone that is structurally similar to parathyroid hormone (PTH). It is produced by various tissues in the body, including the parathyroid glands, bones, and certain cancers.
PTHrP plays a key role in regulating calcium and phosphate levels in the blood, similar to PTH. It helps to maintain a balance of calcium and phosphate in the body by acting on the bones, kidneys, and intestines.
In addition to its role in calcium and phosphate regulation, PTHrP is also involved in the development and growth of various tissues and organs, such as the bone, mammary gland, and lung. It has also been implicated in certain diseases, including cancer and hyperparathyroidism.
Abnormal levels of PTHrP can lead to various health problems, such as hypercalcemia (high blood calcium levels) or hypocalcemia (low blood calcium levels). Treatment for disorders related to PTHrP usually involves addressing the underlying cause, such as surgery for hyperparathyroidism or chemotherapy for PTHrP-producing cancers.
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